I found this thread that offers some guidance to the problem you are seeing.
"Rodrigo Ferreira" <rjrferreira@gmail.com> wrote in message
news:%23hNwBxQ9FHA.3132@TK2MSFTNGP12.phx.gbl...
> Anyone help me with this error!!!!
>
>
>
>
> Server Error in '/multiqual' Application.
> --------------------------------------------------------------------------------
>
> Failed to access IIS metabase.
> Description: An unhandled exception occurred during the execution of the
> current web request. Please review the stack trace for more information
> about the error and where it originated in the code.
>
> Exception Details: System.Web.Hosting.HostingEnvironmentException: Failed
> to
> access IIS metabase.
>
> The process account used to run ASP.NET must have read access to the IIS
> metabase (e.g. IIS://servername/W3SVC). For information on modifying
> metabase permissions, please see
>
http://support.microsoft.com/?kbid=267904. >
> Source Error:
>
>
> An unhandled exception was generated during the execution of the
> current web request. Information regarding the origin and location of the
> exception can be identified using the exception stack trace below.
>
>
> Stack Trace:
>
>
> [HostingEnvironmentException: Failed to access IIS metabase.]
> System.Web.Configuration.MetabaseServerConfig.MapPathCaching(String
> siteID, VirtualPath path) +688
>
> System.Web.Configuration.MetabaseServerConfig.System.Web.Configuration.IConfigMapPath.MapPath(String
> siteID, VirtualPath vpath) +9
> System.Web.Hosting.HostingEnvironment.MapPathActual(VirtualPath
> virtualPath, Boolean permitNull) +173
> System.Web.CachedPathData.GetConfigPathData(String configPath) +398
> System.Web.CachedPathData.GetConfigPathData(String configPath) +263
> System.Web.CachedPathData.GetVirtualPathData(VirtualPath virtualPath,
> Boolean permitPathsOutsideApp) +166
> System.Web.Configuration.RuntimeConfig.GetLKGRuntimeConfig(VirtualPath
> path) +187
>
>
>
>
>
> --------------------------------------------------------------------------------
>
> Version Information: Microsoft .NET Framework Version:2.0.50727.42;
> ASP.NET
> Version:2.0.50727.42
>
>
>