I have a XML load function, then a function which parse the XML data into an
array. This array populates variables which get displayed in dynamic text field
boxes. When I make a call to run all this, it will not refresh the data when
ran on IE on a PC. It works fine on Netscape (mac & PC) and on IE on the
mac. The data will be updated if I close out the window, clear the cache and
run the app again. Any clues as to what might be happening on IE on the PC?

You have to clear the cache of IE or go to "C:\Documents and Settings\*your user profilename*\Local Settings\Temporary Internet Files"